SCHEMBL9301408

SCHEMBL9301408

CN1C(C)(C)CC(NCC(=O)NN)CC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
CTSD P07339 1/20 0.31
ATM Q13315 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8333479 0.84 POLB (0.40) MEN1KMT2APOLBHTTKDM4E
SCHEMBL9366706 0.81 TSHR (0.34) HDAC4HDAC6
SCHEMBL28475922 0.79 ITGB3 (0.33) HDAC4HDAC6
SCHEMBL9544888 0.79 GAA (0.37) MEN1KMT2APOLBHTTKDM4E
SCHEMBL9300620 0.79 HTT (0.41) POLBHTTKDM4EMAPTCTSD
SCHEMBL8335975 0.78 GAA (0.44) MEN1KMT2APOLBHTTKDM4E
SCHEMBL10743893 0.78 TSHR (0.37) HDAC4HDAC6
SCHEMBL10740515 0.74 KMT2A (0.32) MEN1KMT2AHTT
SCHEMBL536355 0.74
SCHEMBL8336929 0.74 HDAC4 (0.36) KMT2AKDM4EHDAC4HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238609-B2 Dicarboxylic acid monomers and methods of making and using the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-19 US disclosed
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-26 US disclosed
US-20150322200-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 US disclosed
US-8633265-B2 UV stabilization of isosorbide polycarbonates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-21 US disclosed
CN-103328570-A UV stabilization of isosorbide polycarbonates SABIC INNOVATIVE PLASTICS IP 2013-09-25 CN disclosed
US-20120184651-A1 UV Stabilization of Isosorbide Polycarbonates SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-07-19 US disclosed
US-RE34791-E Polymer bound hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1994-11-15 US disclosed
EP-0303987-B1 POLYMER BOUND HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-10-14 EP disclosed
US-4978699-A Reaction product of hindered amine with primary amine or reactive hydrazide group and halogenated cyclic anhydride; for extrusion with polymers ATOCHEM NORTH AMERICA, INC. (US) 1990-12-18 US disclosed
US-4975489-A Heating an anhydride-containing polymer with a hydrazine derivative of a 2,2,6,6-tetramethyl-4-aminopiperidine in an inert solvent of by melt blending ATOCHEM NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
US-4857595-A Polymer bound hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-08-15 US disclosed
US-4824884-A Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-04-25 US disclosed
EP-0303282-A2 Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME PGD, CDA, PPIA MEN1 2424/4885KMT2A 1712/4885POLB 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.