Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22398868 | 0.94 | SIGMAR1 (0.46) | GAAHSD17B10ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8675042 | 0.94 | CHRM5 (0.49) | GAAHSD17B10ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL28997961 | 0.92 | CHRM5 (0.47) | GAAHSD17B10ALDH1A1CHRM5CHRM3 | |
| Pyrrolidine SCHEMBL4661508 | 0.89 | CHRM5 (0.52) | HSD17B10CHRM5CHRM3SIGMAR1CA2 | |
| SCHEMBL8507105 | 0.89 | HSD17B10 (0.47) | GAAHSD17B10ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL2916592 | 0.88 | SIGMAR1 (0.50) | HSD17B10CHRM5CHRM3SIGMAR1 | |
| SCHEMBL935078 | 0.88 | SIGMAR1 (0.50) | HSD17B10CHRM5CHRM3SIGMAR1 | |
| SCHEMBL9232046 | 0.88 | CHRM5 (0.50) | GAAHSD17B10ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL15150 | 0.87 | GAA (0.58) | GAAHSD17B10ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL10942934 | 0.87 | GAA (0.58) | GAAHSD17B10ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612313-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993010091-A2 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |