SCHEMBL935078

SCHEMBL935078

O=C(O)CN1CCCNCCN(CC(=O)O)CCCNCC1

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.50
CHRM5 P08912 2/20 0.50
CHRM3 P20309 2/20 0.50
CXCR4 P61073 7/20 0.48
HSD17B10 Q99714 1/20 0.45
MEN1 O00255 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM1 P11229 1/20 0.43
ADRA2C P18825 1/20 0.43
CCR2 P41597 1/20 0.43
CXCL12 P48061 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2916592 1.00 SIGMAR1 (0.50) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL29223244 0.98 CXCR4 (0.52) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL24177173 0.98 SIGMAR1 (0.49) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL934649 0.96 CXCR4 (0.55) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL5134779 0.96 CXCR4 (0.55) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL13805257 0.96 SIGMAR1 (0.48) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL8675042 0.94 CHRM5 (0.49) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL8507105 0.94 HSD17B10 (0.47) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
Pyrrolidine SCHEMBL4661508 0.94 CHRM5 (0.52) SIGMAR1CHRM5CHRM3CXCR4HSD17B10
SCHEMBL28997961 0.92 CHRM5 (0.47) SIGMAR1CHRM5CHRM3CXCR4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025199636-A1 TARGETED RADIOLIGAND COMPOUNDS AND USES THEREOF MCMASTER UNIVERSITY (CA) 2025-10-02 WO claimed
EP-4556029-A2 RADIOPHARMACEUTICAL CONJUGATE The South African Nuclear Energy Corporation Limited (ZA) 2025-05-21 EP claimed
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2025-03-27 US claimed
US-20250026739-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2025-01-23 US claimed
EP-4479040-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF Full-Life Technologies HK Limited (HK) 2024-12-25 EP claimed
US-20240382630-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2024-11-21 US claimed
US-12145926-B2 Compounds and radioligands for targeting neurotensin receptor and uses thereof FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-11-19 US claimed
EP-4436979-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies HK Limited (HK) 2024-10-02 EP claimed
US-20240287046-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-08-29 US claimed
CN-118451091-A Cleavable radioligands for targeting cell surface receptors and uses thereof 辐联科技香港有限公司 2024-08-06 CN claimed
EP-2453927-B1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES UNIV DENMARK TECH DTU (DK) 2019-05-15 EP claimed
EP-2651447-B1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS UNIV DENMARK TECH DTU (DK) 2018-08-29 EP claimed
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE UNIVERSITY OF CAPE TOWN (ZA) 2017-10-19 US claimed
US-20160158392-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2016-06-09 US claimed
US-9226984-B2 Entrapment of radionuclides in nanoparticle compositions Technical University of Denmark and Rigshospitalet (DK) 2016-01-05 US claimed
US-8920775-B2 Loading technique for preparing radionuclide containing nanoparticles TECHNICAL UNIVERSITY OF DENMARK (DK) 2014-12-30 US claimed
EP-2651447-A1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS Technical University of Denmark (DK) 2013-10-23 EP claimed
US-20130251630-A1 Entrapment of Radionuclides in Nanoparticle Compositions RIGSHOSPITALET (DK) 2013-09-26 US claimed
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES RIGSHOSPITALET (DK) 2012-08-23 US claimed
WO-2012079582-A1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS TECHNICAL UNIVERSITY OF DENMARK (DK) 2012-06-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250026739-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF NTSR1, NTSR2, NPSR1 SIGMAR1 145/4885CHRM5 683/4885CHRM3 346/4885
US-20240382630-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR SIGMAR1 278/4885CHRM5 1306/4885CHRM3 642/4885
US-20240287046-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF NTSR1, NTSR2, NPSR1 SIGMAR1 151/4885CHRM5 717/4885CHRM3 368/4885
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR SIGMAR1 278/4885CHRM5 1306/4885CHRM3 642/4885
US-12145926-B2 Compounds and radioligands for targeting neurotensin receptor and uses thereof NTSR1, NTSR2, NPSR1 SIGMAR1 151/4885CHRM5 717/4885CHRM3 368/4885
US-20120213698-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES LIPG, NPC1L1, CD47 SIGMAR1 2820/4885CHRM5 4141/4885CHRM3 4721/4885
US-20170296684-A1 RADIOPHARMACEUTICAL CONJUGATE FOLH1, EPRS1, FOLR1 SIGMAR1 2051/4885CHRM5 2820/4885CHRM3 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.