Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559356 | 0.78 | BRPF1 (0.52) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL1714249 | 0.77 | CA12 (0.39) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL23346692 | 0.77 | BRPF1 (0.50) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL3107572 | 0.77 | MAPT (0.50) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL11286560 | 0.77 | BRPF1 (0.50) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL11274030 | 0.77 | BRPF1 (0.50) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL98218 | 0.76 | CYP19A1 (0.54) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL30448891 | 0.76 | BRPF1 (0.40) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL3099860 | 0.76 | BRPF1 (0.40) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL3345804 | 0.76 | BRPF1 (0.40) | CA12CA9BRPF1BRD4KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54063087-A | — | — | None | — | — | JP | disclosed |
| EP-0420511-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-08-17 | — | — | EP | disclosed |
| US-5302594-A | Antiinflammatory agents; antiallergenic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-04-12 | — | — | US | disclosed |
| US-5221677-A | For treating diseases mediated by leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-22 | — | — | US | disclosed |
| EP-0420511-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-03 | — | — | EP | disclosed |
| JP-S5463087-A | 8-FLUORO-1-METHYLCARBOSTYRYL AND FUNGICIDE FOR RICE PLANT CONTAINING THE SAME | SUMITOMO CHEM CO LTD | 1979-05-21 | — | — | JP | disclosed |