Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 16/20 | 0.43 |
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316843 | 0.97 | KDM4E (0.47) | KDM4EPPARGPPARARARGRXRA | |
| SCHEMBL9316742 | 0.81 | KDM4E (0.48) | KDM4EPPARGPPARAFFAR1HPGD | |
| SCHEMBL9317044 | 0.80 | LMNA (0.47) | KDM4EPPARGPPARARARGRXRA | |
| SCHEMBL8981657 | 0.79 | MAPT (0.47) | KDM4EPPARGPPARA | |
| SCHEMBL8981674 | 0.79 | MAPT (0.47) | KDM4EPPARGPPARA | |
| SCHEMBL8981684 | 0.79 | MAPT (0.47) | KDM4EPPARGPPARA | |
| SCHEMBL9721218 | 0.79 | PPARG (0.55) | PPARGPPARA | |
| Darglitazone SCHEMBL37497 | 0.78 | PPARG (0.48) | KDM4EPPARGPPARAFFAR1 | |
| Darglitazone SCHEMBL20125582 | 0.78 | PPARG (0.48) | KDM4EPPARGPPARAFFAR1 | |
| Darglitazone SCHEMBL9436449 | 0.78 | PPARG (0.48) | KDM4EPPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389699-B1 | Thiazolidinedione derivatives as hypoglycemic agents | PFIZER (US) | 1994-05-11 | — | — | EP | disclosed |