Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.68 |
| ▸ | DRD2 | P14416 | 12/20 | 0.68 |
| ▸ | HTR1A | P08908 | 9/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750987 | 0.91 | HTR2A (0.61) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6748037 | 0.88 | HTR2A (0.58) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6744476 | 0.88 | DRD2 (0.57) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL4884339 | 0.87 | HTR1A (0.61) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6748875 | 0.86 | HTR2A (0.56) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6746157 | 0.86 | HTR2A (0.57) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6744944 | 0.86 | HTR2A (0.56) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6751034 | 0.85 | HTR2A (0.55) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6747860 | 0.84 | HTR2A (0.54) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL9366415 | 0.84 | HTR2A (0.70) | HTR2ADRD2HTR1AKCNH2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409435-B1 | Heteroaryl piperazine antipsychotic agents | PFIZER (US) | 1994-10-26 | — | — | EP | disclosed |
| US-5350747-A | Heteroaryl piperazine antipsychotic agents | PFIZER INC (US) | 1994-09-27 | — | — | US | disclosed |
| WO-1991000863-A1 | HETEROARYL PIPERAZINE ANTIPSYCHOTIC AGENTS | PFIZER INC. (US) | 1991-01-24 | — | — | WO | disclosed |