Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415349 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL2809243 | 0.86 | MAPT (0.56) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL1086028 | 0.86 | KMT2A (0.56) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL10451708 | 0.85 | TSHR (0.43) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL9371067 | 0.85 | MAPT (0.47) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL1720659 | 0.84 | KMT2A (0.54) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL9365836 | 0.82 | MAPT (0.44) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL3907317 | 0.82 | MAPT (0.44) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL9367269 | 0.82 | MAPT (0.44) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL10925924 | 0.79 | MAPT (0.56) | ALDH1A1HPGDMAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368464-B1 | Thiopene-2 carboxamide derivatives and their pharmaceutical use | LILLY SA (ES) | 1994-02-02 | — | — | EP | disclosed |
| US-5021449-A | N-pyrrolidinyl-3 alkyloxythienyl-2-carboxamides; antiemetics, antidepressants, schizophrenia | LILLY S.A. (ES) | 1991-06-04 | — | — | US | disclosed |
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0368464-A1 | Thiopene-2 carboxamide derivatives and their pharmaceutical use | LILLY S.A. (ES) | 1990-05-16 | — | — | EP | disclosed |
| US-4871864-A | Carbamoyloxythiophene fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4839381-A | FUNGICIDES, PESTICIDES; RICE PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| EP-0207355-B1 | ALKOXYCARBONYL-SUBSTITUTED HYDROXYTHIOPHENE CARBOXAMIDES | BAYER AG (DE) | 1988-10-19 | — | — | EP | disclosed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4757085-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| US-4752607-A | Alkoxycarbonyl-substituted hydroxythiophene-carboxamides, fungicidal compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-21 | — | — | US | disclosed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | disclosed |
| EP-0207355-A1 | Alkoxycarbonyl-substituted hydroxythiophene carboxamides | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |