Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367309 | 0.82 | ALDH1A1 (0.49) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL3907317 | 0.81 | MAPT (0.44) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9371067 | 0.80 | MAPT (0.47) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9524469 | 0.79 | KMT2A (0.42) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9365836 | 0.77 | MAPT (0.44) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL1086028 | 0.77 | KMT2A (0.56) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL1720659 | 0.74 | KMT2A (0.54) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9826167 | 0.74 | MAPT (0.48) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL20892464 | 0.72 | MAPT (0.47) | MAPTTSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL2809243 | 0.72 | MAPT (0.56) | MAPTTSHRHSD17B10KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361961-B1 | Organic componds and their use as pharmaceuticals | LILLY SA (ES) | 1994-02-02 | — | — | EP | disclosed |
| US-5041461-A | Organic compounds and their use as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1991-08-20 | — | — | US | disclosed |