Sugi Predict

Sugi Predict / Compounds / SCHEMBL9366201

SCHEMBL9366201

SCHEMBL9366201

COC(Cn1cc(OC(c2ccccc2)c2ccccc2)c(=O)cc1C=O)OC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ P2RX7 Q99572 6/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ HDAC4 P56524 1/20 0.30
▸ HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9369739 0.83 GAA (0.39) ALDH1A1
SCHEMBL9367369 0.81 COMT (0.36) P2RX7HDAC4HDAC8
SCHEMBL9366298 0.81 LTB4R (0.34) ALDH1A1
SCHEMBL9367375 0.81 GAA (0.35) ALDH1A1
SCHEMBL9366575 0.81 HTR6 (0.38) ALDH1A1
SCHEMBL9367213 0.79 CRHBP (0.36) ALDH1A1
SCHEMBL9367489 0.79 APP (0.37) ALDH1A1HDAC4HDAC8
SCHEMBL9371976 0.79 GRIN2B (0.35) ALDH1A1
SCHEMBL9367174 0.78 LMNA (0.31) ALDH1A1
SCHEMBL9366445 0.77 HDAC4 (0.33) HDAC4HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349340-B1 Novel cephem compound, method for producing the same and anti-bacterial agent MEIJI SEIKA CO (JP) 1994-09-07 — — EP disclosed
US-4988686-A Cephalosporin antibiotics MEIJI SEIKA KABUSHIKI KAISHA (JP) 1991-01-29 — — US disclosed
EP-0349340-A2 Novel cephem compound, method for producing the same and anti-bacterial agent MEIJI SEIKA KABUSHIKI KAISHA (JP) 1990-01-03 — — EP disclosed