Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805109 | 0.92 | S1PR2 (0.62) | MAOAHTR2AS1PR2S1PR4S1PR1 | |
| SCHEMBL3266047 | 0.92 | S1PR2 (0.59) | MAOAHTR2AS1PR2S1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL1979100 | 0.90 | S1PR2 (0.57) | MAOAHTR2AS1PR2S1PR4S1PR1 | |
| SCHEMBL3585497 | 0.88 | HTR2A (0.56) | MAOAHTR2AS1PR2S1PR4S1PR1 | |
| SCHEMBL7622782 | 0.86 | MAOA (0.54) | MAOAHTR2AS1PR2S1PR4S1PR1 | |
| SCHEMBL11134033 | 0.82 | S1PR2 (0.51) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL8634823 | 0.82 | EPHX1 (0.64) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL4890813 | 0.81 | MAOA (0.59) | MAOAHTR2AS1PR2S1PR4S1PR1 | |
| SCHEMBL6820062 | 0.80 | S1PR2 (0.53) | MAOAHTR2AS1PR2S1PR4S1PR1 | |
| SCHEMBL11098738 | 0.80 | S1PR2 (0.49) | MAOAHTR2AS1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290377-B1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0290377-A1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-11-09 | — | — | EP | disclosed |