Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10436202 | 0.98 | MAOA (0.57) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL28307957 | 0.92 | MAOA (0.57) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL28163522 | 0.91 | MAOA (0.67) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL28306964 | 0.91 | MAOA (0.55) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL28307956 | 0.91 | MAOA (0.55) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL28163398 | 0.89 | MAOA (0.64) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL11805109 | 0.85 | S1PR2 (0.62) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL28163397 | 0.85 | MAOA (0.63) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL3585497 | 0.84 | HTR2A (0.56) | MAOAS1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL4895850 | 0.84 | EPHX1 (0.56) | MAOAS1PR2S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402673-B2 | Diamine β2 adrenergic receptor agonists | THERAVANCE, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-20080039495-A1 | Diamine Beta2 Adrenergic Receptor Agonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2008-02-14 | — | — | US | disclosed |
| EP-1751086-A2 | DIAMINE ß2 ADRENERGIC RECEPTOR AGONISTS | Theravance, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005121065-A2 | DIAMINE β2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE, INC. (US) | 2005-12-22 | — | — | WO | disclosed |
| US-20050272769-A1 | Diamine beta2 adrenergic receptor agonists | THERAVANCE, INC. (US) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272769-A1 | Diamine beta2 adrenergic receptor agonists | ADRB2, ADRB1, ADRA2C | MAOA 294/4885S1PR2 99/4885S1PR4 230/4885 |
| US-20080039495-A1 | Diamine Beta2 Adrenergic Receptor Agonists | ADRB2, ADRB1, ADRA2C | MAOA 294/4885S1PR2 99/4885S1PR4 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.