Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445358 | 0.80 | MAPT (0.60) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13185627 | 0.77 | RAB9A (0.57) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9800143 | 0.76 | PTGS1 (0.48) | PTGS1PTGS2KMT2AMEN1RAB9A | |
| SCHEMBL13167588 | 0.76 | LMNA (0.57) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27366585 | 0.73 | MAPK1 (0.55) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3857134 | 0.72 | GAA (0.47) | KMT2ARAB9APOLBALDH1A1ALOX15 | |
| SCHEMBL17205660 | 0.72 | NAMPT (0.65) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31453067 | 0.72 | MAPT (0.49) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8607008 | 0.71 | NAMPT (0.67) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8195491 | 0.71 | USP2 (0.51) | RAB9ASMN1; SMN2NPC1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374048-B1 | 4-Aminophenol derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5047555-A | Antiallergens, Antiinflammatory Agents | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |