Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098781 | 0.87 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9367339 | 0.87 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL9853211 | 0.86 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9367111 | 0.86 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9853206 | 0.86 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9028206 | 0.85 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9367482 | 0.85 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9371367 | 0.84 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9367467 | 0.84 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9367746 | 0.84 | ALOX5 (0.52) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420511-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-08-17 | — | — | EP | claimed |
| EP-0420511-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-03 | — | — | EP | claimed |
| JP-3130281-A | — | — | None | — | — | JP | disclosed |
| EP-0420511-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-08-17 | — | — | EP | disclosed |
| US-5302594-A | Antiinflammatory agents; antiallergenic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-04-12 | — | — | US | disclosed |
| US-5221677-A | For treating diseases mediated by leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-22 | — | — | US | disclosed |
| JP-H03130281-A | HETEROCYCLIC DERIVATIVE, PREPARATION OF THE SAME, AND PHARMACOLOGICAL COMPOSITION FOR DISEASE CAUSED BY LEUKOTRIENE, AND MEDICAL TREATMENT OF THE SAME | ICI PHARMA | 1991-06-04 | — | — | JP | disclosed |
| EP-0420511-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-03 | — | — | EP | disclosed |