Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747532 | 0.89 | ALDH1A1 (0.62) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL14597256 | 0.85 | KMT2A (0.73) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL13290672 | 0.85 | KMT2A (0.73) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL11800172 | 0.83 | MAPT (0.76) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL13430940 | 0.82 | MEN1 (0.52) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL14107227 | 0.80 | MEN1 (0.54) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL131175 | 0.80 | MAPT (1.00) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL574042 | 0.80 | MAPT (1.00) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL29354111 | 0.80 | MAPT (1.00) | KMT2AMAPTMEN1KDM4ELMNA | |
| SCHEMBL6707273 | 0.78 | MAPT (0.94) | KMT2AMAPTMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612500-B2 | Heat labile foam-in-place polyurethane foam | BATTELLE SAVANNAH RIVER ALLIANCE LLC (US) | 2026-04-28 | — | — | US | disclosed |
| US-20240141127-A1 | HEAT LABILE FOAM-IN-PLACE POLYURETHANE FOAM | UNITED STATES DEPARTMENT OF ENERGY | 2024-05-02 | — | — | US | disclosed |
| EP-0398472-B1 | Biodegradable polyurethanes | ONO PHARMACEUTICAL CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5225514-A | Azo containing polyurethanes for drug delivery to the large intestines | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612500-B2 | Heat labile foam-in-place polyurethane foam | PUF60, OGG1, EIF3L | KMT2A 4114/4885MAPT 1661/4885MEN1 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.