Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038840 | 0.83 | KIF11 (0.40) | NOTUMTMPRSS4PTPN1TRPV4 | |
| SCHEMBL21776816 | 0.83 | KIF11 (0.40) | NOTUMTMPRSS4PTPN1TRPV4 | |
| SCHEMBL16955243 | 0.80 | NOTUM (0.39) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL403023 | 0.80 | TRPV4 (0.53) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL5546385 | 0.80 | MAPT (0.41) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL31026088 | 0.80 | TRPV4 (0.53) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL4927725 | 0.78 | KIF11 (0.41) | NOTUMPTPN1TRPV4 | |
| SCHEMBL30967278 | 0.78 | KIF11 (0.41) | NOTUMPTPN1TRPV4 | |
| SCHEMBL9793597 | 0.78 | AR (0.39) | PTPN1TRPV4 | |
| SCHEMBL20929103 | 0.76 | FFAR4 (0.37) | SMN1; SMN2PTPN1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1096449-C | Process for preparing substituted arylpyrazoles | BAYER AG (DE) | 2002-12-18 | — | — | CN | claimed |
| EP-0480795-B1 | Benzofuran derivatives, procedure of their preparation, novel intermediates obtained, and their application as pesticides | ROUSSEL UCLAF (FR) | 1994-09-07 | — | — | EP | disclosed |
| US-5182295-A | Miticides, fungicides | ROUSSEL UCLAF (FR) | 1993-01-26 | — | — | US | disclosed |
| EP-0480795-A1 | Benzofuran derivatives, procedure of their preparation, novel intermediates obtained, and their application as pesticides | ROUSSEL-UCLAF (FR) | 1992-04-15 | — | — | EP | disclosed |