Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30038200 | 0.84 | KDM4E (0.49) | KDM4EMAPTGAATSHRMAPK1 | |
| SCHEMBL3544080 | 0.84 | KDM4E (0.49) | KDM4EMAPTGAATSHRMAPK1 | |
| SCHEMBL10850560 | 0.81 | KDM4E (0.44) | KDM4EMAPTGAATSHRHTT | |
| SCHEMBL9367201 | 0.81 | ALDH1A1 (0.42) | KDM4EMAPTGAATSHRMAPK1 | |
| SCHEMBL10498338 | 0.80 | MAPT (0.46) | KDM4EMAPTGAATSHRMAPK1 | |
| SCHEMBL9187870 | 0.80 | TSHR (0.44) | KDM4EMAPTGAATSHRMAPK1 | |
| SCHEMBL11142948 | 0.79 | GAA (0.52) | KDM4EMAPTGAATSHRMAPK1 | |
| SCHEMBL9447622 | 0.79 | KDM4E (0.45) | KDM4EMAPTGAATSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL10497798 | 0.79 | MAPT (0.45) | KDM4EMAPTGAATSHRMAPK1 | |
| SCHEMBL14864863 | 0.78 | MAPT (0.45) | KDM4EMAPTGAATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |