Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10850560 | 0.86 | KDM4E (0.44) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL31721282 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL3534512 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL9187870 | 0.81 | TSHR (0.44) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL9367884 | 0.81 | KDM4E (0.45) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL9814427 | 0.79 | GAA (0.46) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL9368212 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL10498338 | 0.78 | MAPT (0.46) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL9677331 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL9447622 | 0.76 | KDM4E (0.45) | ALDH1A1MAPTKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0251014-B1 | 2-TRIFLUOROMETHYL BENZIMIDAZOLES | BAYER AG (DE) | 1992-05-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0251014-A2 | 2-Trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |