Phenamazoline

Phenamazoline

SCHEMBL936813

c1ccc(NCC2=NCCN2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 1.00
MAOB P27338 3/20 1.00
NISCH Q9Y2I1 2/20 1.00
ADRA1A P35348 12/20 0.63
ADRA1D P25100 10/20 0.63
ADRA2B P18089 8/20 0.63
ADRA2C P18825 8/20 0.63
ADRA2A P08913 6/20 0.63
ADRA1B P35368 9/20 0.59
LMNA P02545 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
TSHR P16473 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18330525 0.83 MAOA (0.71) MAOAMAOBNISCHADRA1AADRA1D
SCHEMBL4794839 0.83 MAOA (0.71) MAOAMAOBNISCHADRA1AADRA1D
SCHEMBL3173010 0.83 MAOA (0.71) MAOAMAOBNISCHADRA1AADRA1D
SCHEMBL11163458 0.81 NISCH (0.68) MAOAMAOBNISCHADRA1AADRA1D
SCHEMBL3169152 0.81 MAOA (0.68) MAOAMAOBNISCHADRA1AADRA1D
SCHEMBL11167612 0.80 MAOA (0.67) MAOAMAOBNISCHADRA1AADRA1D
Hydrochloric Acid SCHEMBL11164250 0.80 NISCH (0.66) MAOAMAOBNISCHADRA1AADRA1D
Hydrochloric Acid SCHEMBL11173544 0.78 NISCH (0.63) MAOAMAOBNISCHADRA1AADRA1D
SCHEMBL17886788 0.78 ADRA1A (1.00) MAOAMAOBNISCHADRA1AADRA1D
SCHEMBL11257533 0.78 MAOA (0.62) MAOAMAOBNISCHADRA1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2025129358-A1 STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES INTELGENX CORP. (CA) 2025-06-26 WO disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
EP-2276467-B1 ALPHA AND BETA ADRENERGIC RECEPTOR AGONISTS FOR TREATMENT OF PAIN AND/OR INFLAMMATION WARSAW ORTHOPEDIC INC (US) 2018-11-07 EP disclosed
US-9763966-B2 Fluocinolone formulations in a biodegradable polymer carrier WARSAW ORTHOPEDIC, INC. (US) 2017-09-19 US disclosed
WO-2016105448-A1 IMIDAZOLINE RECEPTOR TYPE 1 LIGANDS FOR USE AS THERAPEUTICS RIDEOUT DARRYL (US) 2016-06-30 WO disclosed
EP-0058635-B1 SUBSTITUTED 2-ANILINOMETHYL-2 IMIDAZOLIN DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR PESTICIDAL APPLICATION CIBA-GEIGY AG (CH) 1985-07-03 EP disclosed
US-4414223-A MITICIDWS BURROUGHS WELLCOME CO. (US) 1983-11-08 US disclosed
US-4379147-A Substituted 2-(anilinomethyl)-2-imidazoline derivatives, compositions containing these derivatives, and the use thereof for combating pests CIBA-GEIGY CORPORATION (US) 1983-04-05 US disclosed
US-4379147-A Substituted 2-(anilinomethyl)-2-imidazoline derivatives, compositions containing these derivatives, and the use thereof for combating pests CIBA-GEIGY CORPORATION (US) 1983-04-05 US disclosed
US-4379147-A Substituted 2-(anilinomethyl)-2-imidazoline derivatives, compositions containing these derivatives, and the use thereof for combating pests CIBA-GEIGY CORPORATION (US) 1983-04-05 US disclosed
EP-0058635-A1 Substituted 2-anilinomethyl-2 imidazolin derivatives, process for their preparation, agents containing them and their pesticidal application CIBA-GEIGY AG (CH) 1982-08-25 EP disclosed
EP-0058635-A1 Substituted 2-anilinomethyl-2 imidazolin derivatives, process for their preparation, agents containing them and their pesticidal application CIBA-GEIGY AG (CH) 1982-08-25 EP disclosed
EP-0004561-B1 UREA AND AMIDE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICALS CONTAINING THEM AND THEIR USE FOR PREPARING PHARMACEUTICAL COMPOSITIONS CIBA-GEIGY AG (CH) 1981-11-04 EP disclosed