Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.72 |
| ▸ | MRGPRX4 | Q96LA9 | 14/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.65 |
| ▸ | RELA | Q04206 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406160 | 0.91 | NR4A2 (0.87) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL27654975 | 0.90 | NR4A2 (0.70) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL1122713 | 0.88 | NR4A2 (0.94) | NR4A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL4138759 | 0.87 | NR4A2 (0.81) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL10919187 | 0.85 | CYP4F2 (0.70) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL27654979 | 0.85 | NR4A2 (0.72) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL30207018 | 0.84 | NR4A2 (1.00) | NR4A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL339009 | 0.84 | NR4A2 (1.00) | NR4A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL27588719 | 0.84 | BCHE (0.62) | NR4A2SMN1; SMN2 | |
| SCHEMBL9538429 | 0.84 | MRGPRX4 (1.00) | NR4A2MRGPRX4TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1861560-A | Carboxylic acid derivant, its preparation process and pharmaceutical composition | SHANGHAI PHARMACEUTICAL INST C (CN) | 2006-11-15 | — | — | CN | claimed |
| CN-1861560-A | Carboxylic acid derivant, its preparation process and pharmaceutical composition | SHANGHAI PHARMACEUTICAL INST C (CN) | 2006-11-15 | — | — | CN | disclosed |