Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373051 | 0.82 | MAPT (0.64) | MAPTALDH1A1HTTKDM4ELMNA | |
| SCHEMBL9373047 | 0.82 | MAPT (0.64) | MAPTALDH1A1HTTKDM4ELMNA | |
| SCHEMBL9373058 | 0.82 | MAPT (0.64) | MAPTALDH1A1HTTKDM4ELMNA | |
| SCHEMBL6980307 | 0.81 | MAPT (0.62) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL9374432 | 0.79 | USP2 (0.74) | MAPTALDH1A1HTTKDM4ELMNA | |
| SCHEMBL9372639 | 0.79 | USP2 (0.74) | MAPTALDH1A1HTTKDM4ELMNA | |
| SCHEMBL9374438 | 0.79 | USP2 (0.74) | MAPTALDH1A1HTTKDM4ELMNA | |
| SCHEMBL28876262 | 0.78 | KMT2A (0.70) | MAPTKDM4ELMNAL3MBTL1GFER | |
| SCHEMBL9973629 | 0.78 | CTRC (0.59) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11186049 | 0.77 | ALDH1A1 (0.66) | MAPTALDH1A1KDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | claimed |
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-4895947-A | Process for producing 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0322691-A1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |