Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 5/20 | 0.37 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2149020 | 0.81 | DAO (0.41) | OGTNOS1NOS2F2CFD | |
| SCHEMBL5544046 | 0.79 | NOS1 (0.46) | OGTNOS1NOS2F2CFD | |
| SCHEMBL522732 | 0.78 | NOS1 (0.44) | OGTNOS1NOS2F2CFD | |
| SCHEMBL19405967 | 0.78 | OGT (0.37) | OGTNOS1NOS2F2CFD | |
| SCHEMBL5544040 | 0.78 | OGT (0.37) | OGTNOS1NOS2F2CFD | |
| SCHEMBL9370667 | 0.78 | NOS1 (0.41) | OGTNOS1NOS2F2CFD | |
| SCHEMBL1250234 | 0.73 | PSMB8 (0.61) | OGTNOS1NOS2F2CFD | |
| SCHEMBL31381757 | 0.72 | NOS1 (0.33) | OGTNOS1NOS2NOS3 | |
| SCHEMBL14534370 | 0.70 | NOS1 (0.44) | OGTNOS1NOS2F2CFD | |
| SCHEMBL18586859 | 0.70 | OGT (0.37) | OGTNOS1NOS2F2CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385664-B1 | Antiinflammatory benzoxazolones | PFIZER (US) | 1994-01-12 | — | — | EP | disclosed |
| US-5086062-A | Inhibitors of lipoxygenase and-or cyclooxygenase enzymes | PFIZER INC. (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0385664-A2 | Antiinflammatory benzoxazolones | PFIZER INC. (US) | 1990-09-05 | — | — | EP | disclosed |