Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21487595 | 0.89 | GPR35 (0.41) | GPR35MEN1KMT2AALDH1A1TTR | |
| SCHEMBL707416 | 0.81 | SMN1; SMN2 (0.51) | GPR35MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11825523 | 0.77 | GPR35 (0.51) | GPR35MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL21865751 | 0.77 | CYP1A2 (0.46) | GPR35MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8074925 | 0.77 | TSHR (0.50) | GPR35MEN1KMT2AALDH1A1TTR | |
| SCHEMBL31226585 | 0.77 | TSHR (0.50) | GPR35MEN1KMT2AALDH1A1TTR | |
| SCHEMBL9723044 | 0.76 | TDP1 (0.41) | GPR35MEN1KMT2AALDH1A1TTR | |
| SCHEMBL30577358 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL10976593 | 0.76 | ALDH1A1 (0.37) | GPR35MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1192876 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0368008-A1 | Fluorine-containing phenols | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |