Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.67 |
| ▸ | DRD2 | P14416 | 6/20 | 0.65 |
| ▸ | DRD1 | P21728 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 7/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HTR7 | P34969 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373187 | 0.90 | DRD3 (0.68) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9369214 | 0.88 | DRD3 (0.68) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9049140 | 0.83 | HTR1A (0.56) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL31013504 | 0.81 | HTR1A (0.71) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9370364 | 0.81 | HTR1A (0.71) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9372589 | 0.81 | HTR1A (0.69) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9369437 | 0.80 | KCNH2 (0.59) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9372806 | 0.79 | HTR1A (0.67) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9368923 | 0.78 | PRMT5 (0.47) | DRD3DRD2DRD1HTR1A | |
| SCHEMBL9374506 | 0.78 | KCNH2 (0.56) | DRD3DRD2DRD1HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5071845-A | Psychotropic or anxyiolytic agent | SUNTORY LIMITED (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |