Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023866 | 0.84 | PRMT5 (0.46) | PRMT5WDR77HTR1ASLC6A4DRD3 | |
| SCHEMBL9024811 | 0.83 | PRMT5 (0.46) | PRMT5WDR77HTR1ASLC6A4DRD3 | |
| SCHEMBL9173037 | 0.80 | HTR7 (0.37) | HTR1ADRD3DRD1DRD2PKM | |
| SCHEMBL11985664 | 0.79 | PRMT5 (0.49) | PRMT5WDR77TNIKTSHRMAPK1 | |
| SCHEMBL38653482 | 0.79 | PRMT5 (0.51) | PRMT5WDR77KMT2APKMTSHR | |
| SCHEMBL31033174 | 0.79 | PRMT5 (0.49) | PRMT5WDR77DRD3DRD2KMT2A | |
| SCHEMBL9369658 | 0.78 | DRD3 (0.67) | HTR1ADRD3DRD1DRD2 | |
| SCHEMBL9369214 | 0.77 | DRD3 (0.68) | HTR1ADRD3DRD1DRD2KCNH2 | |
| SCHEMBL9373187 | 0.77 | DRD3 (0.68) | HTR1ADRD3DRD1DRD2KCNH2 | |
| SCHEMBL9024164 | 0.76 | SIGMAR1 (0.50) | KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5071845-A | Psychotropic or anxyiolytic agent | SUNTORY LIMITED (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |