Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370128 | 0.87 | GRM2 (0.45) | GRM2ALDH1A1ADORA3ADORA2AADORA2B | |
| SCHEMBL9373426 | 0.84 | GRM2 (0.56) | GRM2ALDH1A1PKMPOLBADORA3 | |
| Hydrochloric Acid SCHEMBL9375536 | 0.83 | GRM2 (0.55) | GRM2ALDH1A1PKMPOLBADORA3 | |
| SCHEMBL9369141 | 0.82 | GRM2 (0.54) | GRM2ALDH1A1PKMPOLBADORA3 | |
| SCHEMBL9368312 | 0.75 | GRM2 (0.56) | GRM2ALDH1A1PKMPOLBADORA3 | |
| SCHEMBL9369054 | 0.71 | GRM2 (0.42) | GRM2ALDH1A1POLBADORA3ADORA2A | |
| SCHEMBL9370038 | 0.71 | ADORA3 (0.42) | GRM2ALDH1A1ADORA3ADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL9368834 | 0.70 | GRM2 (0.41) | GRM2ALDH1A1POLBADORA3ADORA2A | |
| SCHEMBL9735164 | 0.69 | ALDH1A1 (0.44) | GRM2ALDH1A1PKMPOLBADORA3 | |
| Hydrochloric Acid SCHEMBL9735017 | 0.68 | ALDH1A1 (0.43) | GRM2ALDH1A1PKMPOLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399653-B1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | WELLCOME FOUND (GB) | 1994-10-19 | — | — | EP | claimed |
| US-5240937-A | Treatment of epilepsy | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | claimed |
| EP-0399653-A1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-11-28 | — | — | EP | claimed |
| US-5240937-A | Treatment of epilepsy | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0399653-A1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |