Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375302 | 0.90 | HTR2A (0.46) | DRD2HTR2AMCHR1HTR1ADRD4 | |
| SCHEMBL9372598 | 0.89 | HTR1A (0.52) | DRD2HTR2AMCHR1HTR1A | |
| SCHEMBL9369887 | 0.88 | DRD2 (0.45) | DRD2HTR2AMCHR1HTR1A | |
| SCHEMBL9375348 | 0.86 | DRD2 (0.56) | DRD2HTR2AHTR1A | |
| SCHEMBL9374271 | 0.86 | HTR1A (0.46) | DRD2HTR2AMCHR1HTR1A | |
| SCHEMBL9370364 | 0.86 | HTR1A (0.71) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL9371937 | 0.86 | DRD2 (0.67) | DRD2HTR2AMCHR1HTR1ADRD4 | |
| SCHEMBL31013504 | 0.86 | HTR1A (0.71) | DRD2HTR2AHTR1ADRD4DRD3 | |
| SCHEMBL9369796 | 0.85 | HTR1A (0.49) | DRD2HTR2AMCHR1HTR1A | |
| SCHEMBL9372589 | 0.85 | HTR1A (0.69) | DRD2HTR2AHTR1ADRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |