Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | TK2 | O00142 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370733 | 1.00 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL5930585 | 0.87 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL5930446 | 0.87 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL22819195 | 0.87 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL1471401 | 0.86 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL9371154 | 0.86 | TK1 (0.56) | LMNABLMTK1TSHRPMP22 | |
| SCHEMBL9370287 | 0.86 | TK1 (0.56) | LMNABLMTK1TSHRPMP22 | |
| SCHEMBL1471399 | 0.86 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL1468928 | 0.83 | TK1 (0.48) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL769371 | 0.83 | TK1 (0.48) | LMNAALBBLMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394893-B1 | Purinyl and pyrimidinyl tetrahydrofurans | SQUIBB & SONS INC (US) | 1994-06-29 | — | — | EP | claimed |
| EP-0394893-A2 | Purinyl and pyrimidinyl tetrahydrofurans | E.R. SQUIBB & SONS, INC. (US) | 1990-10-31 | — | — | EP | claimed |
| EP-0394893-B1 | Purinyl and pyrimidinyl tetrahydrofurans | SQUIBB & SONS INC (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5164520-A | Chemical intermediates for viricides | E. R. SQUIBB & SONS, INC. (US) | 1992-11-17 | — | — | US | disclosed |
| US-5145960-A | Viricides | E. R. SQUIBB & SONS, INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-5059690-A | Viricides | E. R. SQUIBB & SONS, INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0394893-A2 | Purinyl and pyrimidinyl tetrahydrofurans | E.R. SQUIBB & SONS, INC. (US) | 1990-10-31 | — | — | EP | disclosed |