Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.41 |
| ▸ | TUBB | P07437 | 5/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817877 | 0.75 | PTAFR (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7817882 | 0.75 | PTAFR (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7817886 | 0.75 | PTAFR (0.45) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7023416 | 0.74 | PTAFR (0.56) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7023428 | 0.74 | PTAFR (0.56) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7023424 | 0.74 | PTAFR (0.56) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL9371987 | 0.73 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9203827 | 0.72 | PTAFR (0.50) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7815160 | 0.70 | PTAFR (0.47) | PTAFRACHEPTPN1KMT2AMEN1 | |
| SCHEMBL7815158 | 0.70 | PTAFR (0.47) | PTAFRACHEPTPN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334809-B1 | Agents for the protection of plants against diseases | CIBA GEIGY AG (CH) | 1994-06-15 | — | — | EP | claimed |
| EP-0574510-A4 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | INNOVATIVE TECH CENTER (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0574510-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015294-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1992-09-17 | — | — | WO | disclosed |