Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664375 | 0.99 | ACAT1 (0.58) | ACAT1SOAT1 | |
| SCHEMBL9664425 | 0.94 | KDM4E (0.58) | — | |
| SCHEMBL9213347 | 0.93 | ACAT1 (0.66) | ACAT1SOAT1 | |
| SCHEMBL9212895 | 0.93 | ACAT1 (0.66) | ACAT1SOAT1 | |
| SCHEMBL9217701 | 0.93 | ACAT1 (0.66) | ACAT1SOAT1 | |
| SCHEMBL9210387 | 0.91 | KDM4E (0.64) | ACAT1SOAT1 | |
| SCHEMBL8476295 | 0.90 | KDM4E (0.62) | — | |
| SCHEMBL9215059 | 0.88 | KDM4E (0.64) | — | |
| SCHEMBL9209249 | 0.86 | ACAT1 (0.60) | ACAT1SOAT1 | |
| SCHEMBL8103993 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372445-B1 | Imidazoles for the treatment of atherosclerosis | DU PONT MERCK PHARMA (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0372445-A1 | Imidazoles for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |