Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370570 | 0.99 | ACAT1 (0.60) | ACAT1SOAT1 | |
| SCHEMBL9664425 | 0.96 | KDM4E (0.58) | KDM4E | |
| SCHEMBL9210387 | 0.93 | KDM4E (0.64) | ACAT1SOAT1KDM4E | |
| SCHEMBL8476295 | 0.91 | KDM4E (0.62) | KDM4E | |
| SCHEMBL9213347 | 0.91 | ACAT1 (0.66) | ACAT1SOAT1KDM4E | |
| SCHEMBL9217701 | 0.91 | ACAT1 (0.66) | ACAT1SOAT1KDM4E | |
| SCHEMBL9212895 | 0.91 | ACAT1 (0.66) | ACAT1SOAT1KDM4E | |
| SCHEMBL9215059 | 0.90 | KDM4E (0.64) | KDM4E | |
| SCHEMBL9215071 | 0.86 | KDM4E (0.68) | KDM4E | |
| SCHEMBL9347989 | 0.85 | KDM4E (0.59) | ACAT1SOAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519996-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |
| EP-0505481-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991013876-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| WO-1991009030-A1 | 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-06-27 | — | — | WO | disclosed |