Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069862 | 0.81 | KDM1A (0.42) | MAOBCYP11B2PTGS2CYP11B1GPR84 | |
| SCHEMBL2302098 | 0.78 | MAOA (0.43) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL11726679 | 0.78 | PTGS2 (0.41) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL7641888 | 0.78 | MAOA (0.39) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL27369696 | 0.78 | MAOA (0.39) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL27531503 | 0.77 | MAOA (0.42) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL30667090 | 0.75 | PTGS2 (0.39) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL22557426 | 0.74 | MAOB (0.40) | MAOAMAOBCYP11B2CYP11B1TRPA1 | |
| SCHEMBL21694405 | 0.74 | MAOA (0.40) | MAOAMAOBCYP11B2PTGS2CYP11B1 | |
| SCHEMBL15356383 | 0.74 | PTGS2 (0.38) | MAOAMAOBCYP11B2PTGS2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | claimed |