Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650552 | 0.82 | STING1 (0.43) | SLC2A1STING1FFAR4POLBF13A1 | |
| SCHEMBL23090401 | 0.80 | HSD17B10 (0.51) | SLC2A1RXRARXRBRXRGHTT | |
| SCHEMBL15802564 | 0.77 | RXRG (0.48) | FFAR4RXRARXRBRXRGPOLB | |
| SCHEMBL4267107 | 0.75 | STING1 (0.46) | STING1HTTNPSR1 | |
| SCHEMBL20563708 | 0.74 | TAAR1 (0.58) | SLC2A1 | |
| SCHEMBL9370660 | 0.74 | RXRA (0.44) | FFAR4RXRARXRBRXRG | |
| SCHEMBL27788117 | 0.74 | POLB (0.60) | POLB | |
| SCHEMBL11489161 | 0.74 | SLC2A1 (0.51) | SLC2A1 | |
| SCHEMBL10835634 | 0.73 | PPARA (0.47) | FFAR4 | |
| SCHEMBL7827237 | 0.73 | NPSR1 (0.55) | STING1FFAR4NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425946-B1 | Iso- and heterocyclic phenylsulphonamides | BAYER AG (DE) | 1994-08-17 | — | — | EP | disclosed |
| US-5264458-A | Antithrombotic iso- and heterocyclic phenylsulphonamides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-23 | — | — | US | disclosed |
| US-5191092-A | ANTITHROMBOTIC ISO- AND HETEROCYCLIC PHENYLSULPHONAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0425946-A2 | Iso- and heterocyclic phenylsulphonamides | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |