Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 4/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23090369 | 0.86 | SLC2A1 (0.53) | SLC2A1CYP3A4ALDH1A1NPSR1HTT | |
| SCHEMBL11420544 | 0.80 | HSD17B10 (0.67) | HSD17B10CYP3A4GAAALDH1A1TSHR | |
| SCHEMBL9370651 | 0.80 | SLC2A1 (0.58) | SLC2A1NPSR1HTTPOLBRXRA | |
| SCHEMBL27917034 | 0.77 | CYP3A4 (0.71) | HSD17B10CYP3A4GAAALDH1A1TSHR | |
| SCHEMBL28611348 | 0.77 | HSD17B10 (0.62) | HSD17B10CYP3A4GAAALDH1A1TSHR | |
| SCHEMBL13332559 | 0.75 | HSD17B1 (0.51) | HSD17B10SLC2A1CYP3A4ALDH1A1TSHR | |
| SCHEMBL23090381 | 0.75 | KMT2A (0.42) | HSD17B10SLC2A1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL23090368 | 0.75 | DHODH (0.53) | HSD17B10SLC2A1CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL16527104 | 0.74 | HSD17B10 (0.59) | HSD17B10CYP3A4GAAALDH1A1TSHR | |
| SCHEMBL23090392 | 0.73 | KMT2A (0.41) | SLC2A1ALDH1A1HTTDHODHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE | 2021-03-18 | — | — | US | disclosed |
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE | 2021-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | ZC3HAV1, MAVS, ZC3HAV1L | HSD17B10 1907/4885SLC2A1 3161/4885CYP3A4 1900/4885 |
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | ZC3HAV1, MAVS, ZC3HAV1L | HSD17B10 1907/4885SLC2A1 3161/4885CYP3A4 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.