Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374294 | 0.89 | OXER1 (0.51) | OXER1HTR6MCL1AKR1C3AKR1C2 | |
| SCHEMBL5444461 | 0.82 | OXER1 (0.64) | OXER1HTR6MCL1KMT2AKDM4E | |
| SCHEMBL9538788 | 0.82 | OXER1 (0.44) | OXER1MCL1ALDH1A1ADRA1D | |
| SCHEMBL9368697 | 0.81 | OXER1 (0.56) | OXER1HTR6MCL1KMT2AL3MBTL1 | |
| SCHEMBL9538924 | 0.81 | OXER1 (0.46) | OXER1HTR6MCL1HTR1AHTR1D | |
| SCHEMBL9376615 | 0.81 | MRGPRX4 (0.53) | OXER1ALDH1A1THRB | |
| SCHEMBL9154226 | 0.80 | OXER1 (0.55) | OXER1HTR6MCL1KMT2AL3MBTL1 | |
| SCHEMBL9369149 | 0.80 | OXER1 (0.45) | OXER1HTR6MCL1HTR1AHTR1D | |
| SCHEMBL9373201 | 0.80 | OXER1 (0.53) | OXER1HTR6MCL1AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL9156117 | 0.79 | OXER1 (0.54) | OXER1HTR6MCL1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |