Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374294 | 0.91 | OXER1 (0.51) | OXER1KMT2AMEN1HTR6BLM | |
| SCHEMBL9539117 | 0.84 | OXER1 (0.52) | OXER1KMT2AMEN1HTR6BLM | |
| SCHEMBL5444461 | 0.83 | OXER1 (0.64) | OXER1KMT2AHTR6MCL1KDM4E | |
| SCHEMBL9368601 | 0.82 | OXER1 (0.46) | OXER1KMT2AMEN1HTR6BLM | |
| SCHEMBL9538738 | 0.81 | SRD5A1 (0.47) | OXER1KMT2AMEN1HTR6 | |
| SCHEMBL9154277 | 0.80 | OXER1 (0.55) | OXER1KMT2AMEN1HTR6MCL1 | |
| SCHEMBL9370683 | 0.80 | OXER1 (0.51) | OXER1KMT2AHTR6MCL1AKR1C3 | |
| SCHEMBL9538732 | 0.79 | SRD5A2 (0.49) | OXER1KMT2AMEN1HTR6MCL1 | |
| SCHEMBL9368881 | 0.79 | KMT2A (0.45) | OXER1KMT2AMEN1HTR6BLM | |
| SCHEMBL9368604 | 0.78 | OXER1 (0.46) | OXER1KMT2AHTR6BLMMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |