Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038906 | 0.87 | ELANE (0.42) | ELANEKDM1ABRD4CA2GPR119 | |
| SCHEMBL11245161 | 0.79 | ELANE (0.47) | ELANE | |
| SCHEMBL9375710 | 0.78 | — | — | |
| SCHEMBL486023 | 0.77 | ELANE (0.62) | ELANEKDM1ACA2GPR119 | |
| SCHEMBL5468257 | 0.76 | ALDH1A1 (0.40) | ELANECA2 | |
| SCHEMBL1451808 | 0.76 | KDM4E (0.44) | — | |
| SCHEMBL14814745 | 0.75 | ELANE (0.51) | ELANEKDM1ACA2GPR119 | |
| SCHEMBL8028975 | 0.72 | ELANE (0.41) | ELANEKDM1A | |
| SCHEMBL9375714 | 0.72 | — | — | |
| SCHEMBL11422532 | 0.72 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | claimed |