Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | HTR3B | O95264 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 2/20 | 0.54 |
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
| ▸ | NOS2 | P35228 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370900 | 1.00 | HTR3E (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6547586 | 0.81 | HTR3E (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9367211 | 0.80 | ATM (0.65) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13818953 | 0.80 | ATM (0.65) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9367215 | 0.80 | ATM (0.65) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11378646 | 0.78 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11378649 | 0.78 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL11776533 | 0.77 | TAAR1 (0.69) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL12201109 | 0.74 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL15164585 | 0.74 | GAA (0.58) | NPC1RAB9AMEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239391-B1 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-4871751-A | 1,2,6-Triphenyl-4(1H)-pyridinone derivatives, and their use as fungicides | KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4757081-A | Agriculture, horticulture | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |