Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371279 | 0.89 | MAPT (0.56) | FAAHNPY5RCNR2ROCK1ROCK2 | |
| SCHEMBL9371263 | 0.88 | NPC1 (0.68) | FAAHNPY5RCNR2ROCK1ROCK2 | |
| SCHEMBL9375272 | 0.88 | LMNA (0.60) | FAAHNPY5RCNR2ROCK1ROCK2 | |
| SCHEMBL9371629 | 0.88 | ABL1 (0.61) | FAAHROCK1ROCK2MAPTLMNA | |
| SCHEMBL9375834 | 0.88 | LMNA (0.60) | ROCK1ROCK2MAPTLMNASMN1; SMN2 | |
| SCHEMBL9371439 | 0.86 | FAAH (0.66) | FAAHNPY5RCNR2ROCK1ROCK2 | |
| SCHEMBL9374001 | 0.86 | LMNA (0.78) | FAAHNPY5RCNR2ROCK1ROCK2 | |
| SCHEMBL9378414 | 0.86 | HDAC3 (0.55) | FAAHNPY5RCNR2ROCK1ROCK2 | |
| SCHEMBL9371139 | 0.86 | MEN1 (0.58) | FAAHNPY5RCNR2ROCK1ROCK2 | |
| SCHEMBL9374874 | 0.86 | ABL1 (0.64) | FAAHROCK1ROCK2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589985-A1 | 2-AMINO-4-ARYL-THIAZOLES WITH ANTIASTHMATIC AND ANTI-INFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993000342-A1 | 2-AMINO-4-ARYL-THIAZOLES WITH ANTIASTHMATIC AND ANTI-INFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-01-07 | — | — | WO | disclosed |
| EP-0519449-A1 | 2-Amino-4-aryl thiazoles with antiasthmatic and antiinflammatory activities on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-23 | — | — | EP | disclosed |