Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13202235 | 0.86 | ACHE (0.58) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL8083585 | 0.86 | POLB (0.69) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL13202079 | 0.84 | ACHE (0.57) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL8095237 | 0.84 | ACHE (0.57) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL13486978 | 0.84 | POLB (0.67) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL1573660 | 0.84 | ACHE (0.57) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL1569306 | 0.84 | ACHE (0.60) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL13197086 | 0.82 | ACHE (0.55) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL8091541 | 0.82 | POLB (0.55) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL4231048 | 0.82 | SMN1; SMN2 (0.62) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326106-B1 | Alkylene diamines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5025033-A | Alkylene diamines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| EP-0326106-A2 | Alkylene diamines | Takeda Chemical Industries, Ltd. (JP) | 1989-08-02 | — | — | EP | disclosed |