SCHEMBL8095237

SCHEMBL8095237

CCCCCCN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.57
ALOX5 P09917 1/20 0.54
POLB P06746 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA9 Q16790 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13202079 1.00 ACHE (0.57) ACHEALOX5POLBCA12CA1
SCHEMBL1573660 1.00 ACHE (0.57) ACHEALOX5POLBCA12CA1
SCHEMBL13202235 0.99 ACHE (0.58) ACHEALOX5POLBCA12CA1
SCHEMBL1569306 0.94 ACHE (0.60) ACHEALOX5POLBCA12CA1
SCHEMBL8090142 0.88 ACHE (0.62) ACHEALOX5CA12CA1CA2
SCHEMBL13486978 0.86 POLB (0.67) ACHEALOX5POLBCA12CA1
SCHEMBL13197092 0.85 ACHE (0.54) ACHEALOX5POLBCA12CA1
SCHEMBL9370970 0.84 ALOX5 (0.56) ACHEALOX5POLBCA12CA1
SCHEMBL8083585 0.84 POLB (0.69) ACHEALOX5POLBCA12CA1
SCHEMBL13197086 0.84 ACHE (0.55) ACHEALOX5POLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1059291-A2 Process for preparing bis(ether anhydrides) GENERAL ELECTRIC COMPANY (US) 2000-12-13 EP disclosed
US-6008374-A REACTING N-ALKYL NITROPHTHALIMIDE AND A BISPHENOL ALKALI METAL SALT TO FORM BISIMIDE, EXTRACTING THE FORMED BISIMIDE GENERAL ELECTRIC COMPANY (US) 1999-12-28 US disclosed
US-5936099-A N-ALKYL PHTHALAMIDES BY REACTING LIQUID (C3-C6)ALKYLAMINES AND PHTHALIC ANHYDRIDE; NITRATION FOLLOWED BY REACTING WITH A BISPHENOL A; EXCHANGE REACTION TO FORM DIANHYDRIDE; HYDROLYSIS TO PRODUCE TETRACID MONOMER FOR POLYETHERIMIDES GENERAL ELECTRIC CO. (US) 1999-08-10 US disclosed
EP-0853635-A1 BRANCHED BLOCK ETHYLENE POLYMERS, THEIR PREPARATION AND COMPOSITIONS COMPRISING THE SAME THE DOW CHEMICAL COMPANY (US) 1998-07-22 EP disclosed
WO-1997012919-A1 BRANCHED BLOCK ETHYLENE POLYMERS, THEIR PREPARATION AND COMPOSITIONS COMPRISING THE SAME THE DOW CHEMICAL COMPANY (US) 1997-04-10 WO disclosed
EP-0684232-A1 Process for preparing bis(ether anhydrides) GENERAL ELECTRIC COMPANY (US) 1995-11-29 EP disclosed
US-4960903-A Aromatic compounds having sulfonyl groups TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1990-10-02 US disclosed
EP-0233409-B1 AROMATIC SULFONYL COMPOUNDS Tonen Corporation (JP) 1990-09-26 EP disclosed
EP-0233409-A2 Aromatic sulfonyl compounds Tonen Corporation (JP) 1987-08-26 EP disclosed