Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373635 | 0.85 | CYP19A1 (0.60) | CYP11B1CYP19A1CYP11B2CYP1A2POLB | |
| Hydrochloric Acid SCHEMBL11612301 | 0.83 | CYP19A1 (0.58) | CYP11B1CYP19A1CYP11B2CYP1A2POLB | |
| SCHEMBL6301112 | 0.83 | CYP19A1 (0.61) | CYP11B1CYP19A1 | |
| SCHEMBL6299490 | 0.83 | CYP19A1 (0.61) | CYP11B1CYP19A1 | |
| SCHEMBL11696644 | 0.77 | CYP19A1 (0.59) | CYP11B1CYP19A1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL9374363 | 0.75 | CYP19A1 (0.60) | CYP11B1CYP19A1CYP11B2IDO1 | |
| SCHEMBL11701649 | 0.75 | HMOX1 (0.64) | CYP11B1CYP19A1CYP11B2IDO1 | |
| SCHEMBL10652258 | 0.74 | CYP19A1 (0.69) | CYP11B1CYP19A1CYP11B2CYP1A2POLB | |
| SCHEMBL9368893 | 0.74 | IDO1 (0.53) | CYP19A1CYP1A2CYP3A4MAPTTBXAS1 | |
| SCHEMBL11700389 | 0.73 | CYP17A1 (0.50) | CYP11B1CYP19A1CYP11B2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188383-B1 | Imidazole derivatives, their preparation and therapeutic use | SANKYO CO (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-4894385-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0188383-A2 | Imidazole derivatives, their preparation and therapeutic use | SANKYO COMPANY LIMITED (JP) | 1986-07-23 | — | — | EP | disclosed |