Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367013 | 0.87 | POLB (0.50) | PTGS1PTGS2ALDH1A1MAPTNPSR1 | |
| SCHEMBL9370537 | 0.85 | POLB (0.61) | PTGS1PTGS2ALDH1A1MAPTNPSR1 | |
| SCHEMBL9367490 | 0.85 | POLB (0.65) | PTGS1PTGS2ALDH1A1MAPTNPSR1 | |
| SCHEMBL14516168 | 0.83 | PTGS1 (0.80) | PTGS1PTGS2NPC1PKMRAB9A | |
| SCHEMBL9367598 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2ALDH1A1MAPTNPSR1 | |
| SCHEMBL9367737 | 0.82 | GSTP1 (0.48) | PTGS1PTGS2MAPTRAB9APOLB | |
| SCHEMBL9369861 | 0.81 | POLB (0.53) | PTGS1PTGS2ALDH1A1MAPTNPSR1 | |
| SCHEMBL14497481 | 0.80 | PTGS1 (0.74) | PTGS1PTGS2NPC1PKMRAB9A | |
| SCHEMBL9371933 | 0.79 | POLB (0.42) | PTGS1PTGS2ALDH1A1MAPTNPSR1 | |
| SCHEMBL9371990 | 0.79 | POLB (0.47) | PTGS1PTGS2ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409163-B1 | Novel cyclic vinylogous N-hydroxy-N-methylureas useful as 5-lipoxygenase inhibitors | MERRELL DOW PHARMA (US) | 1994-12-21 | — | — | EP | disclosed |