Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372016 | 1.00 | CES2 (0.36) | CES2CES1SLC6A1TSHRSLC6A11 | |
| SCHEMBL7311926 | 0.98 | CES2 (0.39) | CES2CES1SLC6A1TSHRSLC6A11 | |
| SCHEMBL7311922 | 0.98 | CES2 (0.39) | CES2CES1SLC6A1TSHRSLC6A11 | |
| SCHEMBL9719724 | 0.73 | NPSR1 (0.41) | ALDH1A1 | |
| SCHEMBL31365247 | 0.70 | CES2 (0.43) | CES2CES1SLC6A1TSHRSLC6A11 | |
| SCHEMBL23007747 | 0.70 | CES2 (0.33) | CES2CES1 | |
| Trifluoroacetic Acid SCHEMBL27702588 | 0.69 | CES2 (0.42) | CES2CES1SLC6A1TSHRSLC6A11 | |
| Trifluoroacetic Acid SCHEMBL5722383 | 0.69 | TSHR (0.42) | CES2CES1SLC6A1TSHRSLC6A11 | |
| SCHEMBL8209830 | 0.69 | CES2 (0.48) | CES2CES1TSHRSMN1; SMN2HDAC8 | |
| SCHEMBL9011610 | 0.67 | CES2 (0.46) | CES2CES1TSHRSMN1; SMN2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486385-B1 | Imidazole derivatives, process for their fabrication and pharmaceutical compositions containing them | ADIR (FR) | 1994-12-28 | — | — | EP | disclosed |
| EP-0486385-A1 | Imidazole derivatives, process for their fabrication and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-20 | — | — | EP | disclosed |