SCHEMBL9372159

SCHEMBL9372159

CSCCOC(=O)CSc1cc(/N=c2\sc(=O)n3n2CCCC3)ccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SIGMAR1 Q99720 2/20 0.31
CYP2D6 P10635 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9372164 1.00 CYP1A2 (0.32) CYP1A2TSHRALDH1A1CYP3A4CYP2C9
SCHEMBL9824441 0.90 ALDH1A1 (0.36) CYP1A2TSHRALDH1A1CYP3A4CYP2C9
SCHEMBL9824446 0.90 ALDH1A1 (0.36) CYP1A2TSHRALDH1A1CYP3A4CYP2C9
SCHEMBL9824119 0.89 GAA (0.40) CYP1A2TSHRALDH1A1CYP3A4CYP2C9
SCHEMBL9824127 0.89 GAA (0.40) CYP1A2TSHRALDH1A1CYP3A4CYP2C9
SCHEMBL9824588 0.87 KMT2A (0.38) CYP1A2TSHRALDH1A1CYP3A4CYP2C9
SCHEMBL9824583 0.87 KMT2A (0.38) CYP1A2TSHRALDH1A1CYP3A4CYP2C9
SCHEMBL9375067 0.85 POLB (0.31) GAA
SCHEMBL9375069 0.85 POLB (0.31) GAA
SCHEMBL9377192 0.84 CDC25B (0.39) TSHRALDH1A1ALOX15HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312064-B1 Thiadiazabicyclononane derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO (JP) 1994-05-04 EP disclosed