Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824588 | 1.00 | KMT2A (0.38) | KMT2AALDH1A1MAPTMEN1POLB | |
| SCHEMBL9824119 | 0.90 | GAA (0.40) | KMT2AALDH1A1MEN1POLBRXFP1 | |
| SCHEMBL9824127 | 0.90 | GAA (0.40) | KMT2AALDH1A1MEN1POLBRXFP1 | |
| SCHEMBL9414261 | 0.88 | TDP1 (0.34) | ALDH1A1PRNPRXFP1TDP1SMN1; SMN2 | |
| SCHEMBL9372159 | 0.87 | CYP1A2 (0.32) | ALDH1A1TDP1GAACYP1A2CYP3A4 | |
| SCHEMBL9824446 | 0.87 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTMEN1POLB | |
| SCHEMBL9372164 | 0.87 | CYP1A2 (0.32) | ALDH1A1TDP1GAACYP1A2CYP3A4 | |
| SCHEMBL9824441 | 0.87 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTMEN1POLB | |
| SCHEMBL9375067 | 0.86 | POLB (0.31) | POLBRXFP1GAA | |
| SCHEMBL9375069 | 0.86 | POLB (0.31) | POLBRXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273417-B1 | THIADIAZABICYCLONONANE DERIVATIVES AND HERBICIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |