Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | LIG1 | P18858 | 1/20 | 0.70 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723219 | 0.83 | PKM (1.00) | PKMLIG1PLAUKDM4ERAB9A | |
| SCHEMBL3064091 | 0.81 | PKM (0.68) | PKMLIG1PLAULMNAGSK3B | |
| SCHEMBL23553995 | 0.78 | PLAU (0.59) | PKMLIG1PLAUALDH1A1NR1D1 | |
| SCHEMBL2872059 | 0.78 | GSK3B (0.67) | PKMLMNATSHRGSK3BMAPT | |
| SCHEMBL25256894 | 0.78 | PKM (0.69) | PKMLIG1PLAULMNATSHR | |
| SCHEMBL16879111 | 0.76 | PKM (0.61) | PKMLIG1PLAULMNAGSK3B | |
| SCHEMBL7826596 | 0.75 | USP47 (0.52) | PKMLIG1LMNATSHRGSK3B | |
| SCHEMBL5982145 | 0.74 | PLAU (1.00) | PKMLIG1PLAU | |
| SCHEMBL9141963 | 0.74 | GSK3B (0.51) | PKMLIG1PLAULMNATSHR | |
| SCHEMBL13753593 | 0.74 | PKM (0.58) | PKMLIG1PLAULMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210088814-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS, INC. (CA) | 2021-03-25 | — | — | US | disclosed |
| EP-0588785-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5185363-A | Administering for treatment of inflammatory diseases | ABBOTT LABORATORIES (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0588785-A4 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1991-12-30 | — | — | EP | disclosed |
| WO-1990012008-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-10-18 | — | — | WO | disclosed |