Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374488 | 0.87 | SMN1; SMN2 (0.33) | FDPSFPR2SMN1; SMN2PDE4APDE4B | |
| SCHEMBL5133385 | 0.86 | PDE4A (0.40) | FDPSFPR2SMN1; SMN2PDE4APDE4B | |
| SCHEMBL28701458 | 0.80 | FDPS (0.39) | FDPSSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9369991 | 0.75 | FNTA (0.36) | FDPSSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL1978411 | 0.74 | AGTR1 (0.44) | KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL21858158 | 0.74 | FDPS (0.35) | FDPS | |
| SCHEMBL29269235 | 0.73 | FDPS (0.33) | FDPSSMN1; SMN2KMT2ANPC1POLB | |
| SCHEMBL12467584 | 0.72 | FDPS (0.35) | FDPSKMT2ANPC1POLBL3MBTL1 | |
| SCHEMBL31754121 | 0.72 | FDPS (0.35) | FDPSSMN1; SMN2 | |
| SCHEMBL12480055 | 0.72 | FDPS (0.35) | FDPSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343499-B1 | 3-Pyrrolidinylthio-1-azabicyclo(3,2,0) hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5194624-A | Treatent of infectious diseases in humans and animals | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-16 | — | — | US | disclosed |
| US-4963544-A | THIENAMYCIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0343499-A1 | 3-Pyrrolidinylthio-1-azabicyclo(3,2,0) hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-29 | — | — | EP | disclosed |