Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591709 | 0.86 | CHRNA7 (0.39) | EPHX1GAACHRM2CHRM1 | |
| SCHEMBL10569876 | 0.82 | CHRM1 (0.33) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL10567916 | 0.80 | ALDH1A1 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL261179 | 0.77 | CHRNA7 (0.50) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL260902 | 0.77 | CHRNA7 (0.50) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL260527 | 0.77 | CHRNA7 (0.50) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3314224 | 0.76 | CHRM1 (0.40) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL30581624 | 0.75 | ALDH1A1 (0.49) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9091935 | 0.72 | — | — | |
| SCHEMBL9046323 | 0.71 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261763-B1 | Novel bridged bicyclic N-heterocycles | BEECHAM GROUP PLC (GB) | 1994-02-09 | — | — | EP | disclosed |
| US-4968691-A | TREATMENT AND PREVENTION OF DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1990-11-06 | — | — | US | disclosed |
| EP-0261763-A1 | Novel bridged bicyclic N-heterocycles | BEECHAM GROUP PLC (GB) | 1988-03-30 | — | — | EP | disclosed |