Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374098 | 0.86 | EPHX1 (0.36) | EPHX1CHRM2CHRM1GAA | |
| SCHEMBL9046323 | 0.81 | ALDH1A1 (0.35) | CHRNA7ALDH1A1 | |
| SCHEMBL9046328 | 0.81 | ALDH1A1 (0.35) | CHRNA7ALDH1A1 | |
| SCHEMBL260527 | 0.75 | CHRNA7 (0.50) | CHRNA7ALDH1A1CHRM2MEN1CYP2D6 | |
| SCHEMBL260902 | 0.75 | CHRNA7 (0.50) | CHRNA7ALDH1A1CHRM2MEN1CYP2D6 | |
| SCHEMBL261179 | 0.75 | CHRNA7 (0.50) | CHRNA7ALDH1A1CHRM2MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL30581624 | 0.74 | ALDH1A1 (0.49) | CHRNA7ALDH1A1CHRM2MEN1CYP2D6 | |
| SCHEMBL10569876 | 0.72 | CHRM1 (0.33) | ALDH1A1CHRM2MEN1KMT2ACHRM1 | |
| Hydrochloric Acid SCHEMBL10567916 | 0.71 | ALDH1A1 (0.36) | ALDH1A1CHRM2MEN1KMT2ACHRM1 | |
| SCHEMBL2317693 | 0.69 | CHRNA7 (0.52) | CHRNA7ALDH1A1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339950-A2 | Dibenzofurancarboxamides, their use as pharmaceutical agents, a composition containing the same, and a process for the preparation thereof | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1989-11-02 | — | — | EP | disclosed |