SCHEMBL9374247

SCHEMBL9374247

CCCCCCCCCCCCCCCCCC(=O)OC1CCC(C)(C)N(OCCC(=O)OCCCCOC(=O)CCON2C(C)(C)CCC(OC(=O)CCCCCCCCCCCCCCCCC)C2(C)C)C1(C)C

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.43
NAAA Q02083 3/20 0.42
PRKCA P17252 3/20 0.42
EPHX2 P34913 5/20 0.41
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
DNM1 Q05193 1/20 0.38
HTR2C P28335 1/20 0.37
STAT3 P40763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194536 0.92 NAAA (0.47) DGKANAAAPRKCASTAT3
SCHEMBL194331 0.89 NAAA (0.42) NAAAPRKCAHTR2CSTAT3
SCHEMBL3632141 0.88 NAAA (0.43) NAAA
SCHEMBL3629448 0.84 NAAA (0.39) NAAA
SCHEMBL7069050 0.81 NAAA (0.43) NAAAPRKCASTAT3
SCHEMBL3668155 0.80 NAAA (0.36) NAAAPRKCASTAT3
SCHEMBL14973487 0.80 NAAA (0.36) NAAASTAT3
SCHEMBL4348704 0.78 NAAA (0.49) DGKANAAAPRKCASTAT3
SCHEMBL17931087 0.77 NAAA (0.41) DGKANAAAPRKCAEPHX2
SCHEMBL3161047 0.76 NAAA (0.41) DGKANAAAPRKCAEPHX2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389422-B1 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5015678-A Light stabilized polymers by the addition of N-hydoxyamines CIBA-GEIGY CORPORATION (US) 1991-05-14 US disclosed
EP-0389422-A2 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed